Tarik Skubal earned his major league-leading 15th win, and the Detroit Tigers handed the Chicago White Sox their 99th loss with a 13-4 victory on Saturday night.
Matt Vierling, Colt Keith and Zach McKinstry homered for Detroit, which won for the third time in four games. Keith and Jake Rogers each had three RBIs, and Vierling scored three times.
Skubal (15-4) struck out eight in five innings. He was charged with three runs and eight hits.
Corey Julks had three hits for the White Sox, who moved closer to setting a franchise record for most losses in a season. Chicago dropped a club-worst 106 games in 1970.
The major league record for most losses in a season belongs to the Cleveland Spiders, who went 20-134 in 1899. The 1962 New York Mets hold the modern record of 120 losses.
Ky Bush (0-3) yielded five runs and eight hits in three innings for Chicago in his fourth career start.
The White Sox fell to 3-10 under interim manager Grady Sizemore, who replaced the fired Pedro Grifol on Aug. 8.
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